Since some seem to find anecdotal arguments preferable:
http://www.cozybuilders.org/newsletters/news_83.pdf (see pg 7)
http://freespace.virgin.net/tommy.sandham/twopack.htm
http://www.seqair.com/skunkworks/Too...spirators.html
http://www.ecboards.co.uk/board_chapters/public/chapter12.htm
and of course:
http://en.wikipedia.org/wiki/Bhopal_Disaster
And from the
3M site - FAQ's about their filters:
Can I use organic vapour filters with isocyanate based compounds?
A.
The levels at which isocyanate can be detected by smell or taste are considerably higher than the Maximum Exposure Limit (MEL) as set by the HSE. There would be no indication of smell/taste that 'breakthrough' had occurred until an exposure higher than the MEL.
The safe solution would be to use an air fed system which supplies breathable quality air to the wearer rather than filtering out airborne contaminants. The 3M™ Visionair or S-200 Air Fed Systems could be considered for this type of application .
And for the
stats lovers (PDF file): (emphasis mine)
"Diisocyanate-induced asthma is one of the commonest causes of occupational asthma in many industrial countries. Several follow-up studies, included our own, have demonstrated that symptoms are very persistent for years and may well be permanent.
A small proportion only gets rid of their asthma symptoms. Unspecific bronchial hyperresponsiveness may for years affect normal life and the patients are dependent of occasional or regular medication. Thus, the disease as well as the medical prognosis, indeed, affect the patient in many ways as to some extent elucidated by our study.
For 17% of the patients, the diagnosis caused retirement from working life, 43 % of those who had got the disase considered it to be the direct cause for being outside working life at the time of follow-up.
Only about half of the diseased workers were still working at the time of follow-up. Diisocyanate-induced asthma means almost always a change of employment; only 13% of those who contracted disease were still employed by the same employer.
In conclusion, contracting diisocyanate asthma involves a series of health effects which has far reaching repurcussions not only on the patients health but also on his or her socioeconomic life."